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Erythema Exsudativum Multiforme


Eryhema multiforme is an acute, self-limited condition characterized by the abrupt onset of symmetrical fixed red papules some of which evolve into target lesions. The target lesion is characterized by concentric zones of colour changes with a central dusky or purple zone and an outer red zone. Target lesions will often develop a blister or crust in the central zone after several days. 20% of all cases occur in childhood. The majority of patients with EM have their disease precipitated by herpes simplex virus. Other precipitating factors include mycoplasma pneumoniae and histoplasmosis.




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