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Squamous Cell Carcinoma

Malignant tumour arising from the keratinocytes of the epidermis. It grows in a destructive way and metastasises mainly via the lymphatic system. Several predisposing or pathogenetic factors for the occurrence of this tumour are known including UV-radiation, chronic inflammatory skin changes, chemical carcinogens, immunosuppression and viral infections. The tumour begins with a small, slightly raised, warty, grey or brownish hyperkeratosis and enlarges in time. The growth can progress rapidly when extensive ulcerative necrosis occur. On the lips or genitalia the presenting sign may be a fissure or small erosion or ulcer which fails to heal and bleeds recurrently.

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