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Infantile Acrolocalised Papulovesicular Syndrome


Self-limited dermatosis of childhood characterized by the abrupt onset of small rose-pink or purple vesicular papules that may be covered with a haemorrhagic crust. The eruption is symmetrically located on the face, limbs, and buttocks. Pruritus is common. This disorder has been reported after various types of viral infections, including Coxsackie, Epstein-Barr virus, and parainfluenza. This disorder presents cutaneous lesions similar to those in papular acrodermatitis of childhood but lacks the characteristic association with hepatitis B virus. It may represent a variant of the latter, although it still remains uncertain if the papulovesicular acro-located syndrome warrants separate classification.




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