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Infectious Mononucleosis


A common, acute, usually self-limited infectious disease caused by the Epstein-Barr virus, characterized by fever, membranous pharyngitis, lymph node and splenic enlargement, lymphocyte proliferation, and the presence of atypical lymphocytes, and giving rise to various immune reactions, including the development of a transient heterophile and a persistent Epstein-Barr virus antibody response. Potential complications include hepatitis and encephalomeningitis. It affects primarily adolescents and young adults, being spread by saliva transfer and possibly other modes; in children the infection is largely subclinical. (Dorland, 27th ed)




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